Anti-parasite drugs 'affect lamb development'
AgResearch scientists have collected the first known data showing behavioural developmental impacts on lambs whose mothers were treated with long-acting drugs for parasites.
The ruling paves the way for use of null segregants for accelerated breeding in horticulture. This is done by using a genetic modification that makes plants produce fruit much sooner than would normally occur. This in turn allows desirable traits, such as resistance to a particular disease, to be developed much faster using traditional, non-GM selective breeding techniques. Null segregant offspring can then be created by breeding out the genetic modification. This would vastly reduce the amount of time to bring a new variety to market.
Opportunities also include enhanced or speed breeding of productive plant species in New Zealand, and use of null segregants in conventional breeding programmes to develop new varieties of NZ-adapted ryegrass, for example.
The EPA has clarified that null segregants are not considered genetically modified organisms under the Hazardous Substances and New Organisms Act 1996.
EPA general manager hazardous substances and new organisms Dr Chris Hill says the decision provides certainty for researchers in our primary industries and brings New Zealand into line with other countries in the OECD, such as Australia and the US.
This will help New Zealand scientists keep pace with international research, Hill says.
"Our experts make independent, evidence-based decisions that take into account the latest research and international best practice," says Hill.
He explains that just as a brown-eyed parent may have a blue-eyed child who did not inherit the gene for brown eyes, plants, animals or other organisms that are descended from genetically modified organisms may not inherit their parents’ genetic modifications. This means the descendants do not contain any genetic modifications.
The introduction of any specific null segregant into the environment will be verified case by case by the Ministry for Primary Industries.
This does not change the regulations for food that contains genetically modified organisms or ingredients derived from genetically modified organisms. These come under the Food Standards Code, overseen by Food Standards Australia New Zealand (FSANZ).
The EPA ruling came after an application led by AgResearch and supported by 14 other research or industry organisations.
“This clarification does not change the way we treat genetically modified organisms used in research in New Zealand, but what it does do is give us clarity on the use of organisms that we saw as being a grey area within the regulations,” says AgResearch science team leader Richard Scott.
“We had a clear view as researchers that these null segregants were not GMOs, but now we have certainty from the EPA to support this.
“The way is now cleared for researchers to consider the opportunities to use null segregants to deliver additional research and benefits to New Zealand’s productive industries and in areas such as health, nutrition, and wellbeing.”
